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  Bio-identical hormones are "plant derived hormones" from precursors found in wild yam or soybean. They are modified in a laboratory to be identical to the hormones produced by the human body. They possess the same exact chemical structure as hormones produced by our body.     Synthetic hormones are "artificial" not found in nature. Chemically altered from     human hormone and not identical in structure or activity to natural human hormones.   Establish your natural hormone levels by getting a baseline test in your late thirties or early pre-menopause.   The manner of replacing the lost hormones varies according to the choices made by the patient and their physician. One choice is using the various synthetic hormones available. The alternate choice is using "" hormones. Should a person take a hormone that is identical to the one that the body produced throughout younger life; thereby being natural to the body, or take one that the body does not recognize as natural, but instead a foreign substance. Because it is foreign, it may possess many side effects or even unknown side effects.

Why Bio-identical Hormone Replacement?   With natural aging comes the natural diminishment of our own body’s production of hormones. As the result, all of the general health we took for granted starts to diminish as well. Causing symptoms such as hot flashes, forgetfulness, anxiety, sleep disruption, low libido, and on and on. Here falls the need for “replacement” hormones. Maintaining this balance is the goal of any type of hormone replacement therapy (HRT). The hormones a woman produces until she reaches menopause protect her heart and bones. Once she is no longer producing these hormones, she is at risk of developing heart disease and osteoporosis. The risks continue to worsen the longer she is without these essential hormones.  

Why is BHRT compounded?   BHRT is available only from a compounding pharmacy, and only with a valid prescription from a doctor. Pharmacy compounding is the art and science of preparing customized medications for patients.  Its practice dates back to the origins of pharmacy. The goal of a compounding pharmacy is the Triad, formed by doctor, pharmacist, and patient.  By working amongst all three, the compounding pharmacy can tailor-make the prescription to fit each individual patient.  The dosage strength and dosage form can be customized to a patients specific needs.  BHRT can be compounded in capsules, topical and vaginal creams, gels, oral liquids, lozenges, vaginal and rectal suppositories, solutions, tablet triturates, rapid dissolve tablet, troches, mini troches, and other dosage forms.  Testosterone can be added if deemed necessary by the doctor and patient for libido problems. Conventional BHRT has few standard dosage forms. hormone replacement is not available commercially.  

What are the benefits with Natural BHRT?  

  • Identical in structure to hormones the human body produces  
  • Provide protective benefits that were originally provided by the body’s naturally occurring hormones  
  •  Far fewer unwanted effects than synthetic hormones  
  •  Improved libido  
  •  Helps in the prevention of osteoporosis and restoration of bone strength  
  •  Protection against heart disease and stroke  
  •  Reduced hot flashes and reduced vaginal dryness  
  •  Muscle mass and strength are better maintained  
  •  Improvement in cholesterol levels  
  •  Risk of depression is reduced  
  •  Reduced risk of breast and endometrial cancer  
  •  Prevention of senility and Alzheimer’s Disease  
  •  Improved sleep  
  •  Mood, concentration, and memory become better  
  •  Over all quality of life is restored/improved  
  •  Side effects are usually dose related and correct when the proper dose is dispensed  
  •  Dosage is adjustable and individualized for the patient’s needs and goals  
  •  Multiple hormones can be combined in one dosage form  
  •  Several dosage forms available; capsules, topical and vaginal creams, gels, oral liquids, lozenges, troches, and more 
  • Can bypass the digestive tract and liver with non-oral dosage forms  

How do you get BHRT?  

  • Get BHRT information and fill out medical history form  
  • Discuss BHRT with prescribing physician and obtain a prescription (or, if necessary, ask a pharmacist for recommendation)  
  • Bring BHRT prescription to Station Pharmacy (call for a pharmacist consult (310)   264-3800) or fax prescription and medical history form to Station Pharmacy at (310) 264-3804)  
  • Get recommendation from compounding pharmacist and coordinate with prescribing physician   Once the patient and the physician have determined that the patient is a candidate for BHRT our compounding pharmacists’ work directly with the patient and the physician to tailor a hormone regimen to “fit” the patient with the appropriate dosage strengths and dosage form. (Generally the physician is a general practitioner, gynecologist, or endocrinologist. If you do not have a physician, or yours is not familiar with BHRT, you can contact a compounding pharmacist for further information) Our compounding pharmacist will have a consultation with the patient using the baseline hormone levels (if available), in some cases a saliva test, along with patient medical history, and patient goals. With that, they will derive the compound that seems appropriate for the patient and send a consultation report to the doctor with recommendations. After the doctor approves or makes changes to the recommendation, the patient starts a three week course and is reviewed by the pharmacist again before continuing therapy. Any adjustments in therapy or consultations are reported to the doctor for review/approval. It usually doesn’t take more than 2-3 months to find the appropriate hormone regimen. The doctor continues to follow the patient at their discretion. The pharmacist follows the hormone regimen regularly, with refills, and communicates any modifications with the physician.  

There are four groups of hormones that are of major concern:  

Estrogens   - The Estrogens include estrone (E1), estradiol (E2), and estriol (E3). Together they are referred to as Tri-Est. In some cases E2 and E3 are combined and referred to as Bi-Est. The plant source of these chemicals is the soybean.  These estrogens are prescribed for replacement therapy due to menopause, ovarian failure or for women who have had a hysterectomy with removal of their ovaries. There are benefits to prescribing the bio-identical hormone replacement of estrogen. When prescribed for menopause, estrogen can alleviate, in most cases hot flashes, vaginal and urinary tract dryness, sleeplessness and mood swings. There are also cardiovascular benefits to replacement therapy. Lastly, hormone replacement therapy can help osteoporosis if treatment is begun early enough.   (Dosing guidelines: Triest 0.3mg-3mg QD-BID)

Progesterone   -  Progesterone is derived from the mexican yam or the soybean. Progesterone can be prescribed for infertility, luteal phase defect, PMS or in combination with estrogens for menopause. Progesterone comes primarily from the ovaries both before and after menopause, but it is also produced in both the brain and peripheral nerves. It prepares and maintains the uterus for pregnancy, by stimulating the uterine lining to thicken with rich, well vascularized tissue to support an embryo. Progesterone also affects the brain by producing a sense of calmness, and its sedating, anti-anxiety effect helps promote rejuvenating sleep. (Dosing guidelines: Progesterone 25mg-800mg QD in divided doses QD-QID)

Testosterone  - Testosterone is a hormone produced by both men and women. It promotes muscle growth, increases energies, elevates mood, strengths bones, helps relieve menopausal symptoms, increases sensitivity to sexual pleasure in nipples and genitals, and enhances sex drive. In women, testosterone is produced in the ovaries, adrenal glands, and to a lesser extent in the skin, brain, and liver. Adequate levels of testosterone can help to prevent heart disease, stroke, vascular disorders such as diabetic blindness, and Osteoporosis. (Dosing guidelines: Testosterone 0.25mg-5mg for women daily, divided doses. Testosterone 2mg-100mg for men daily, divided doses)

Dihydroepiandrosterone (DHEA)  - DHEA (dehydroepiandrosterone) is produced in greater abundance by the adrenal glands than any other hormone. It is also produced to a lesser extent by the ovaries, testes, and brain. The body uses DHEA as a buffer hormone or as a storehouse from which the body can produce other hormones such as estrogens or testosterone when needed (DHEA is often referred to as the “mother hormone”). DHEA research has indicated that this hormone may have important therapeutic benefits is such areas as cardiovascular disease, autoimmune diseases, cancer, chronic fatigues, fibromyalgia, and may have anti-aging properties. (Dosing guidelines: DHEA 2mg-100mg QD)  



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